1. Anti-infection
  2. Bacterial Fungal
  3. Antitubercular agent-21

Antitubercular agent-21 (Compound 15) is an antitubercular agent with an MIC of o.4 µg/mL against M. tuberculosis H37Rv. Antitubercular agent-21 exhibits lower activity against other microorganism such as bacteria gram-positive, gram-negative or fungi. Antitubercular agent-21 shows low cytotoxicity.

For research use only. We do not sell to patients.

Antitubercular agent-21 Chemical Structure

Antitubercular agent-21 Chemical Structure

CAS No. : 2412142-93-7

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Description

Antitubercular agent-21 (Compound 15) is an antitubercular agent with an MIC of o.4 µg/mL against M. tuberculosis H37Rv. Antitubercular agent-21 exhibits lower activity against other microorganism such as bacteria gram-positive, gram-negative or fungi. Antitubercular agent-21 shows low cytotoxicity[1].

Cellular Effect
Cell Line Type Value Description References
B16-F10 IC50
10.98 μg/mL
Compound: 15
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 32061963]
NHDF IC50
36.18 μg/mL
Compound: 15
Cytotoxicity against human NHDF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human NHDF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 32061963]
Molecular Weight

334.44

Formula

C15H22N6OS

CAS No.
SMILES

N/C(C1=NC=CC(N2CCCC2)=C1)=N\NC(N3CCOCC3)=S

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Antitubercular agent-21 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antitubercular agent-21
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HY-147505
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