1. Apoptosis
  2. Ferroptosis Apoptosis
  3. Antitumor agent-125

Antitumor agent-125 (compound 17A) is a novel platinum(IV) prodrug. Antitumor agent-125 can activate the mitochondrion-dependent apoptosis pathway. Antitumor agent-125 induces ferroptosis in HCT-116/OXA.

For research use only. We do not sell to patients.

Antitumor agent-125 Chemical Structure

Antitumor agent-125 Chemical Structure

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Description

Antitumor agent-125 (compound 17A) is a novel platinum(IV) prodrug. Antitumor agent-125 can activate the mitochondrion-dependent apoptosis pathway. Antitumor agent-125 induces ferroptosis in HCT-116/OXA[1].

Molecular Weight

788.11

Formula

C27H33ClN4O9Pt

SMILES

Cl[Pt]12([NH2][C@@H]3CCCC[C@H]3[NH2]1)(OC(COC4=C(C=CC(C(/C=C/C(C(C)=N5)=NC(C)=C5C)=O)=C4)OC)=O)OC(C(O2)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Antitumor agent-125 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antitumor agent-125
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HY-157222
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