2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Antitumor agent-139

Antitumor agent-139 (compound 9b) is a liver - and mitochondria-targeting gold(I) complexe, and produces reactive oxygen species (ROS) and facilitates DNA excretion. Antitumor agent-139 inhibits tumor growth in a patient-derived xenograft model of hepatocellular carcinoma.

For research use only. We do not sell to patients.

Antitumor agent-139 Chemical Structure

Antitumor agent-139 Chemical Structure

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Description

Antitumor agent-139 (compound 9b) is a liver - and mitochondria-targeting gold(I) complexe, and produces reactive oxygen species (ROS) and facilitates DNA excretion. Antitumor agent-139 inhibits tumor growth in a patient-derived xenograft model of hepatocellular carcinoma[1].

Molecular Weight

1269.21

Formula

C64H84AuBrN2O5P
SMILES

C[C@](CC[C@@]1([C@]2(C[C@](C)(CC1)C(OCC#C[Au]C3N(C=CN3CC)CC)=O)[H])C)([C@@]4(CCC5C(C)([C@H](CC[C@@]5(C46)C)OC(CCCCC[P+](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9)=O)C)C)C2=CC6=O.[Br-]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Antitumor agent-139 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-139Antitumor agent139Antitumor agent 139Reactive Oxygen Speciesxenograft model of hepatocellular carcinomareactive oxygen speciesInhibitorinhibitorinhibit

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