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  4. Antitumor agent-144

Antitumor agent-144 (16) is an antitumor agent, with IC50 values of 2.6 μM and 8.4 μM in L1210 and KB cells, respectively.

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Antitumor agent-144 Chemical Structure

Antitumor agent-144 Chemical Structure

CAS No. : 137346-42-0

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Antitumor agent-144 Related Antibodies

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Description

Antitumor agent-144 (16) is an antitumor agent, with IC50 values of 2.6 μM and 8.4 μM in L1210 and KB cells, respectively[1].

Cellular Effect
Cell Line Type Value Description References
KB IC50
7.6 μM
Compound: 17
In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay.
In vitro antitumor activity against human epidermoid carcinoma KB cells by MTT assay.
10.1016/0960-894X(95)00353-U
L1210 IC50
9.6 μM
Compound: 17
In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay.
In vitro antitumor activity against murine lymphoma L1210 cells by MTT assay.
10.1016/0960-894X(95)00353-U
V79 IC50
19 μM
Compound: 13
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under anaerobic conditions
10.1016/0960-894X(95)00352-T
V79 IC50
27 μM
Compound: 13
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions
Differential hypoxic cytotoxicity towards chinese hamster cells (V79) using MTT assay under aerobic conditions
10.1016/0960-894X(95)00352-T
Molecular Weight

446.50

Formula

C25H26N4O4
CAS No.
SMILES

O=C1C2=CC3=C(N(C2=NC(N1C4=CC=CC=C4)=O)CCCCCCCC)C=CC([N+]([O-])=O)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antitumor agent-144 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-144137346-42-0Antitumor agent144Antitumor agent 144OthersantitumorKB cellL1210Inhibitorinhibitorinhibit

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HY-117708
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