2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Antitumor agent-71

Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization.

For research use only. We do not sell to patients.

Antitumor agent-71 Chemical Structure

Antitumor agent-71 Chemical Structure

CAS No. : 2011756-99-1

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Antitumor agent-71 Related Antibodies

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Description

Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization.

IC50 & Target

3.98/15.70/10.48/5.38 μM
In Vitro

Antitumor agent-71 (0.002-20 μM; 48 hours) inhibits the cell line HepG2, MCF-7, MIA PaCa-2, and Bel-7402 growth in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antitumor agent-71 Related Antibodies

Cell Viability Assay

Cell Line: HepG2, MCF-7, MIA PaCa-2, and Bel-7402[1].
Concentration: 0.002-20 μM
Incubation Time: 48h
Result: Showed antitumor activity against HepG2, MIA PaCa-2, MCF-7, and Bel-7402 cell lines with the IC50 values of 3.98/15.70/10.48/5.38 μM.
In Vivo

Antitumor agent-71 (10-20 mg/kg; intravenous injection; twice a day; 20 days) shows inhibitory effects and inhibits HepG2 cell line in nude mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: HepG2 model BALB/c nude mice[1]
Dosage: 10mg/kg, 20mg/kg
Administration: Intravenous injection; twice a day; 20 days
Result: Inhibited tumor growth in a dose-dependent manner.
Molecular Weight

509.62

Formula

C26H31N5O4S
CAS No.
SMILES

O=S(C1=CC2=C(C=C1)N(C)C3=C2C=C(CN4CCN(C)CC4)C=C3)(NC5=CC=C(OC)N=C5OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antitumor agent-71 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-712011756-99-1Antitumor agent71Antitumor agent 71Microtubule/TubulinInhibitorinhibitorinhibit

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