Antitumor photosensitizer-6 

Antitumor photosensitizer-6 (Compound Ru2) shows synergetic type I/II photosensitization and photocatalytic activity upon 595 nm light excitation. Ru2 induces intracellular redox imbalance and affects the biosynthetic and metabolic processes, leading to cell apoptosis. Antitumor photosensitizer-6 can be used for research of photodynamic therapy (PDT)^[1].

2047.44

C₇₄H₄₆F₂₆N₁₄P₄Ru₂S₃

2938922-20-2

FC1=C(C2=CC=C(C3=CC(C4=CC=CC=[N]45)=[N]6[Ru]578([N]9=C(C%10=CC=CC(C%11=CC=CC=[N]8%11)=[N]%107)C=CC=C9)[N]%12=C(C6=C3)C=CC=C%12)S2)C%13=NSN=C%13C(C(S%14)=CC=C%14C%15=CC(C%16=CC=CC=[N]%17%16)=[N]([Ru]%18%19%20%17[N]%21=C(C%22=CC=CC(C%23=CC=CC=[N]%23%19)=[N]%18%22)C=CC=C%21)C(C%24=[N]%20C=CC=C%24)=C%15)=C1F.FP(F)(F)(F)(F)F.FP(F)(F)(F)(F)F.FP(F)(F)(F)(F)F.FP(F)(F)(F)(F)F

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Wang Z, et al. Donor-Acceptor-Donor Strategy Rouses the Photodynamic Therapy Anticancer Activity of a Bis-terpyridyl Ru(II) Complex. J Med Chem. 2024 Aug 8;67(15):13435-13445.  [Content Brief]