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  4. AP-C6

AP-C6 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C6 concentration-dependently inhibits human cGKII activity in vitro. AP-C6 potentiate cAMP signaling by PDE inhibition.

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AP-C6 Chemical Structure

AP-C6 Chemical Structure

CAS No. : 2234276-60-7

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AP-C6 Related Antibodies

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Description

AP-C6 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C6 concentration-dependently inhibits human cGKII activity in vitro. AP-C6 potentiate cAMP signaling by PDE inhibition[1].

IC50 & Target

pIC50: 6.5 (cGKII)[1]
Molecular Weight

281.31

Formula

C15H15N5O
CAS No.
SMILES

OCCNC1=NC=CC(C2=CC=C(N3C=NC=C3)C=C2)=N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AP-C6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AP-C62234276-60-7Othersguanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase IIcGKIIAP-C5Inhibitorinhibitorinhibit

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HY-153542
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