1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. APL-1081

APL-1081 (Mal-Exo-EVC-MMAE) is an ADC Linker that can be used to synthesize antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

APL-1081 Chemical Structure

APL-1081 Chemical Structure

CAS No. : 2921735-80-8

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  • Biological Activity

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Description

APL-1081 (Mal-Exo-EVC-MMAE) is an ADC Linker that can be used to synthesize antibody-drug conjugates (ADCs)[1].

Molecular Weight

1502.79

Formula

C75H115N13O19

CAS No.
SMILES

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OC(C3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCC(O)=O)=O)=O)=O)C(NCCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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APL-1081 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
APL-1081
Cat. No.:
HY-169322
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