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Aplodan  (Synonyms: Creatinol O-phosphate; Creatinol phosphate; Creatinolfosfate)

Cat. No.: HY-107335 Purity: 99.20%
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Aplodan (Creatinol O-phosphate) is an antiischemic and antiarrhythmic agent. Aplodan has a protective action on cell membrane. Aplodan has the potential for the research of ischemic heart or acute myocardial infarction .

For research use only. We do not sell to patients.

Aplodan Chemical Structure

Aplodan Chemical Structure

CAS No. : 6903-79-3

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Based on 1 publication(s) in Google Scholar

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Description

Aplodan (Creatinol O-phosphate) is an antiischemic and antiarrhythmic agent. Aplodan has a protective action on cell membrane. Aplodan has the potential for the research of ischemic heart or acute myocardial infarction [1][2][3][4][5].

Molecular Weight

197.13

Formula

C4H12N3O4P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N=C(N)N(C)CCOP(O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 62.5 mg/mL (317.05 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0728 mL 25.3640 mL 50.7279 mL
5 mM 1.0146 mL 5.0728 mL 10.1456 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.0728 mL 25.3640 mL 50.7279 mL 126.8199 mL
5 mM 1.0146 mL 5.0728 mL 10.1456 mL 25.3640 mL
10 mM 0.5073 mL 2.5364 mL 5.0728 mL 12.6820 mL
15 mM 0.3382 mL 1.6909 mL 3.3819 mL 8.4547 mL
20 mM 0.2536 mL 1.2682 mL 2.5364 mL 6.3410 mL
25 mM 0.2029 mL 1.0146 mL 2.0291 mL 5.0728 mL
30 mM 0.1691 mL 0.8455 mL 1.6909 mL 4.2273 mL
40 mM 0.1268 mL 0.6341 mL 1.2682 mL 3.1705 mL
50 mM 0.1015 mL 0.5073 mL 1.0146 mL 2.5364 mL
60 mM 0.0845 mL 0.4227 mL 0.8455 mL 2.1137 mL
80 mM 0.0634 mL 0.3170 mL 0.6341 mL 1.5852 mL
100 mM 0.0507 mL 0.2536 mL 0.5073 mL 1.2682 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Aplodan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aplodan6903-79-3Creatinol O-phosphateCreatinol CreatinolfosfateOthersantiischemicantiarrhythmicischemic heartventricular premature beatVPBcell membraneInhibitorinhibitorinhibit

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