2. Apoptosis
  3. Apoptosis
  4. Apoptosis inducer 25

Apoptosis inducer 25 (Compound 4H) inhibits the proliferation of cell BGC-823 with IC50 of 0.37 μM. Apoptosis inducer 25 arrests cell cycle at G2/M phase, induces apoptosis in cell BGC-823, and causes mitochondrial dysfunction. Apoptosis inducer 25 exhibits good pharmacokinetic properties in rats.

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Apoptosis inducer 25 Chemical Structure

Apoptosis inducer 25 Chemical Structure

CAS No. : 2763063-15-4

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Description

Apoptosis inducer 25 (Compound 4H) inhibits the proliferation of cell BGC-823 with IC50 of 0.37 μM. Apoptosis inducer 25 arrests cell cycle at G2/M phase, induces apoptosis in cell BGC-823, and causes mitochondrial dysfunction. Apoptosis inducer 25 exhibits good pharmacokinetic properties in rats[1].

Molecular Weight

683.87

Formula

C42H53NO7
CAS No.
SMILES

O=C1C(C#N)=C[C@]2([C@]([H])(C1(C)C)CC[C@](C)(C2=CC3=O)[C@]4([C@]3([C@]5([C@@](C(OCCCCOC(C6=CC=C(C=C6)O)=O)=O)(CC4)CCC(C)(C5)C)[H])[H])C)C
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Apoptosis inducer 25 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptosis inducer 252763063-15-4Apoptosis inducer25Apoptosis inducer-25ApoptosisBGC-823ratInhibitorinhibitorinhibit

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