AR-A014418-d₃ (Synonyms: AR 0133418-d₃; GSK 3β inhibitor VIII-d₃; AR 014418-d₃)

Cat. No.: HY-10512S: FAQs
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AR-A014418-d₃ is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM)[1].

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AR-A014418-d<sub>3</sub> Chemical Structure

AR-A014418-d₃ Chemical Structure

CAS No. : 1216908-63-2

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31
5 mg		Get quote	Estimated Time of Arrival: December 31

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Other Forms of AR-A014418-d₃:

AR-A014418 In-stock

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Description	AR-A014418-d₃ is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM)[1].
Molecular Weight	311.33
Formula	C₁₂H₉D₃N₄O₄S
CAS No.	1216908-63-2
Unlabeled CAS	487021-52-3
SMILES	O=C(NCC1=CC=C(OC([2H])([2H])[2H])C=C1)NC2=NC=C([N+]([O-])=O)S2
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Bhat R, Xue Y, Berg S, Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem. 2003 Nov 14;278(46):45937-45. [Content Brief]

AR-A014418-d₃ Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AR-A014418-d₃1216908-63-2AR 0133418-d₃GSK 3β inhibitor VIII-d₃AR 014418-d₃Isotope-Labeled CompoundsGSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3microglial cell migrationcannabidiolBV-2 cellsguarding behaviourInhibitorinhibitorinhibit

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AR-A014418-d3 (Synonyms: AR 0133418-d3; GSK 3β inhibitor VIII-d3; AR 014418-d3)

Other Forms of AR-A014418-d3:

AR-A014418-d3 Related Antibodies

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AR-A014418-d3 Related Classifications