2. Immunology/Inflammation
  3. CD38
  4. Ara-F-NAD+ sodium

Ara-F-NAD+ sodium is an arabino analogue of NAD+. Ara-F-NAD+ sodium is a potent, reversible and slow-binding CD38 NADase inhibitor.

For research use only. We do not sell to patients.

Ara-F-NAD+ sodium Chemical Structure

Ara-F-NAD+ sodium Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Ara-F-NAD+ sodium Related Antibodies

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Description

Ara-F-NAD+ sodium is an arabino analogue of NAD+. Ara-F-NAD+ sodium is a potent, reversible and slow-binding CD38 NADase inhibitor[1][2].

Molecular Weight

687.40

Formula

C21H25FN7NaO13P2
Appearance

Solid

Color

White to off-white

SMILES

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OC[C@@H]4[C@@H](O)[C@H](F)[C@H]([N+]5=CC=CC(C(N)=O)=C5)O4)([O-])=O)(O[Na])=O)O3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (181.84 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4548 mL 7.2738 mL 14.5476 mL
5 mM 0.2910 mL 1.4548 mL 2.9095 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.4548 mL 7.2738 mL 14.5476 mL 36.3689 mL
5 mM 0.2910 mL 1.4548 mL 2.9095 mL 7.2738 mL
10 mM 0.1455 mL 0.7274 mL 1.4548 mL 3.6369 mL
15 mM 0.0970 mL 0.4849 mL 0.9698 mL 2.4246 mL
20 mM 0.0727 mL 0.3637 mL 0.7274 mL 1.8184 mL
25 mM 0.0582 mL 0.2910 mL 0.5819 mL 1.4548 mL
30 mM 0.0485 mL 0.2425 mL 0.4849 mL 1.2123 mL
40 mM 0.0364 mL 0.1818 mL 0.3637 mL 0.9092 mL
50 mM 0.0291 mL 0.1455 mL 0.2910 mL 0.7274 mL
60 mM 0.0242 mL 0.1212 mL 0.2425 mL 0.6061 mL
80 mM 0.0182 mL 0.0909 mL 0.1818 mL 0.4546 mL
100 mM 0.0145 mL 0.0727 mL 0.1455 mL 0.3637 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Ara-F-NAD+ sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ara-F-NAD+CD38authenticcoenzymesNAD analogueNAD+Inhibitorinhibitorinhibit

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