Arachidonylcyclopropylamide (Synonyms: ACPA)

Cat. No.: HY-110003 Purity: ≥98.0%: FAQs
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Arachidonylcyclopropylamide (ACPA) is a potent and selective CB1 receptors agonist. Arachidonylcyclopropylamide inhibits forskolin-stimulated cAMP production in CHO cells transfected with human cannabinoid CB1 receptors (IC₅₀=2 nM).

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Arachidonylcyclopropylamide Chemical Structure

CAS No. : 229021-64-1

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Description	Arachidonylcyclopropylamide (ACPA) is a potent and selective CB1 receptors agonist. Arachidonylcyclopropylamide inhibits forskolin-stimulated cAMP production in CHO cells transfected with human cannabinoid CB1 receptors (IC₅₀=2 nM)^[1].
In Vitro	Arachidonylcyclopropylamide induces a dose-dependent increase in BV-2 cell migration (EC₅₀=2.2 nM)^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Arachidonylcyclopropylamide Related Antibodies
Molecular Weight	343.55
Formula	C₂₃H₃₇NO
CAS No.	229021-64-1
Appearance	Liquid
Color	Colorless to light yellow
SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1CC1)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (259 KB) SDS (393 KB) COA (237 KB) Handling Instructions (2659 KB)
References	[1]. Franklin A, et al. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. Eur J Pharmacol. 2003;474(2-3):195-198. [Content Brief]

Arachidonylcyclopropylamide Related Classifications

Neurological Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Arachidonylcyclopropylamide229021-64-1ACPACannabinoid ReceptorCB1 receptorsmicroglial cell migrationCHO cellsBV-2 cellsInhibitorinhibitorinhibit

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