2. Anti-infection
  3. Antibiotic
  4. Aranciamycin

Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC503.7*10-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells .

For research use only. We do not sell to patients.

Aranciamycin Chemical Structure

Aranciamycin Chemical Structure

CAS No. : 72389-06-1

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Aranciamycin Related Antibodies

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

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Description

Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC503.7*10-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells [1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
2.7 μM
Compound: 3
Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay
[PMID: 20192240]
HepG2 IC50
18 μM
Compound: 4
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
HL-60 IC50
4.1 μM
Compound: 3
Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay
Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay
[PMID: 20192240]
KB 3-1 IC50
> 30 μM
Compound: 4
Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
NCI-H460 IC50
> 30 μM
Compound: 4
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
SW-620 IC50
> 30 μM
Compound: 4
Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 25789410]
Molecular Weight

544.50

Formula

C27H28O12
CAS No.
SMILES

O=C1[C@@](C)(O)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)OC)C(C(O)=C3C(C4=C5C=CC=C4O)=O)=C1C=C3C5=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Aranciamycin Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aranciamycin72389-06-1Antibioticcollagenase anthracycline antibiotictumor cellsInhibitorinhibitorinhibit

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