1. Peptides
  2. Peptide and Derivatives
  3. Cell-adhesion Peptides Inhibitors and Substrates
  4. Arg-Gly-Asp-Cys TFA

Arg-Gly-Asp-Cys TFA is the binding motif of fibronectin to cell adhesion molecules. Arg-Gly-Asp-Cys TFA can inhibit platelet aggregation and fibrinogen binding.

For research use only. We do not sell to patients.

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Arg-Gly-Asp-Cys TFA Chemical Structure

Arg-Gly-Asp-Cys TFA Chemical Structure

CAS No. : 2171504-22-4

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10 mg USD 132 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Arg-Gly-Asp-Cys TFA is the binding motif of fibronectin to cell adhesion molecules. Arg-Gly-Asp-Cys TFA can inhibit platelet aggregation and fibrinogen binding[1].

In Vitro

Arg-Gly-Asp-Cys-functionalized chitosan (0.25-1 mg/mL; 2-7 days) favors cell growth and an increase in cellular proliferation compared to the control cells (viability >140%)[1].
Arg-Gly-Asp-Cys-functionalizes chitosan derivatives exhibit in vitro wound healing properties by enhancing fibroblast proliferation and adhesion[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

449.48 (free acid)

Formula

C15H27N7O7S.xC2HF3O2

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

RGDC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (Need ultrasonic)

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In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL; Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Arg-Gly-Asp-Cys TFA
Cat. No.:
HY-P0314A
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