2. GPCR/G Protein Neuronal Signaling
  3. GPR119
  4. AS-1669058 free base

AS-1669058 free base is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 free base induces insulin secretion induced by high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 free base improved glucose tolerance and reduced blood glucose levels in db/db mice.

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AS-1669058 free base Chemical Structure

AS-1669058 free base Chemical Structure

CAS No. : 1395553-31-7

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AS-1669058 free base Related Antibodies

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Description

AS-1669058 free base is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 free base induces insulin secretion induced by high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 free base improved glucose tolerance and reduced blood glucose levels in db/db mice.

Molecular Weight

421.24

Formula

C18H15BrF2N4O
CAS No.
SMILES

[O-][N+]1=CC=CC(CCNC2=NC(C3=CC(F)=C(Br)C=C3F)=NC(C)=C2)=C1
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AS-1669058 free base Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AS-16690581395553-31-7AS1669058AS 1669058GPR119G Protein-Coupled Receptor 119Inhibitorinhibitorinhibit

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AS-1669058 free base
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