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  2. Disease Research Fields Plants Phenylpropanoids
  3. Aristolochiaceae Cancer Lignans
  4. Asarum sieboldii Miq.
  5. Asarinin

Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb.

For research use only. We do not sell to patients.

Asarinin Chemical Structure

Asarinin Chemical Structure

CAS No. : 133-05-1

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Based on 1 publication(s) in Google Scholar

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Description

Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 EC50
> 60 μM
Compound: 5
Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay
Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay
[PMID: 22381047]
HepG2 IC50
7.1 μM
Compound: 5
Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis
Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis
[PMID: 22381047]
NIH3T3 IC50
0.2 μM
Compound: 1
Cytotoxicity against murine 3T3 cells by MTT assay
Cytotoxicity against murine 3T3 cells by MTT assay
[PMID: 17253847]
Molecular Weight

354.35

Formula

C20H18O6

CAS No.
SMILES

[H][C@@]12[C@@](CO[C@@H]2C3=CC=C(OCO4)C4=C3)([H])[C@H](C5=CC=C(OCO6)C6=C5)OC1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Asarinin
Cat. No.:
HY-N0701A
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