Asarinin

Cat. No.: HY-N0701A: FAQs
Data Sheet Handling Instructions

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Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb_[1].

For research use only. We do not sell to patients.

Asarinin Chemical Structure

CAS No. : 133-05-1

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Other Forms of Asarinin:

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Purity & Documentation
References
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Description

Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb_[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	EC₅₀	> 60 μM Compound: 5	Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay	[PMID: 22381047]
HepG2	IC₅₀	7.1 μM Compound: 5	Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis	[PMID: 22381047]
NIH3T3	IC₅₀	0.2 μM Compound: 1	Cytotoxicity against murine 3T3 cells by MTT assay Cytotoxicity against murine 3T3 cells by MTT assay	[PMID: 17253847]

Molecular Weight

354.35

Formula

C₂₀H₁₈O₆

CAS No.

133-05-1

SMILES

[H][C@@]12[C@@](CO[C@@H]2C3=CC=C(OCO4)C4=C3)([H])[C@H](C5=CC=C(OCO6)C6=C5)OC1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Guo T, et al.Ultrasound-Assisted Aqueous Two-Phase System for Extraction and Enrichment of Zanthoxylum armatum Lignans. Molecules. 2015 Aug 20;20(8):15273-86. [Content Brief]

Asarinin Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Asarinin133-05-1OthersNatural ProductInhibitorinhibitorinhibit

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