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  6. [Asn23] β-Amyloid (1-40), Iowa mutation

[Asn23] β-Amyloid (1-40), Iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.)

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[Asn23] β-Amyloid (1-40), Iowa mutation Chemical Structure

[Asn23] β-Amyloid (1-40), Iowa mutation Chemical Structure

CAS No. : 374796-72-2

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[Asn23] β-Amyloid (1-40), Iowa mutation Related Antibodies

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Description

[Asn23] β-Amyloid (1-40), Iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.)

Molecular Weight

4328.82

Formula

C194H296N54O57S
CAS No.
Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asn-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Sequence Shortening

DAEFRHDSGYEVHHQKLVFFAENVGSNKGAIIGLMVGGVV
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Purity & Documentation
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[Asn23] β-Amyloid (1-40), Iowa mutation Related Classifications

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[Asn23] β-Amyloid (1-40), Iowa mutation374796-72-2OthersInhibitorinhibitorinhibit

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