2. GPCR/G Protein Neuronal Signaling
  3. MCHR1 (GPR24)
  4. ATC0175 free base

ATC0175 (free base) is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH-R1) with an IC50 value of 3.4 nM, as well as good selectivity over the Y5 and the α2A receptors. ATC0175 (free base) is promising for research of obesity.

For research use only. We do not sell to patients.

ATC0175 free base Chemical Structure

ATC0175 free base Chemical Structure

CAS No. : 509118-03-0

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Description

ATC0175 (free base) is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH-R1) with an IC50 value of 3.4 nM, as well as good selectivity over the Y5 and the α2A receptors. ATC0175 (free base) is promising for research of obesity[1].

Molecular Weight

425.47

Formula

C23H25F2N5O
CAS No.
SMILES

CN(C1=NC(N[C@H]2CC[C@H](CC2)NC(C3=CC(F)=C(C=C3)F)=O)=NC4=C1C=CC=C4)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ATC0175 free base Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATC0175509118-03-0ATC 0175ATC-0175MCHR1 (GPR24)Melanin concentrating hormone receptor 1MCH-R1Y5α2A receptorsobesityInhibitorinhibitorinhibit

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ATC0175 free base
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