2. Inhibitory Antibodies
  3. ATG-031

ATG-031 is a humanised anti-CD24 monoclonal antibody. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the "don't eat me" signals that characterize the growth of many cancers. ATG-031 can be used in the study of haematological malignancies as well as solid tumours.

For research use only. We do not sell to patients.

Size Price Stock Quantity
1 mg USD 350 In-stock
5 mg USD 770 In-stock
10 mg USD 1235 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

ATG-031 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE ATG-031

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Description

ATG-031 is a humanised anti-CD24 monoclonal antibody. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the "don't eat me" signals that characterize the growth of many cancers. ATG-031 can be used in the study of haematological malignancies as well as solid tumours.

Isotype

Human IgG4 kappa
Recommend Isotype Controls
Species

Humanized

IC50 & Target

CD24
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[ATG-031]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Loaded CD24 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78913) on AHC2 biosensor, can bind ATG-031 with an affinity constant of 8.121E-09 M as determined in BLI assay.
  • Immobilized Biotinylated Human CD24, at 5 μg/mL (100 μL/well, HY-P78913) on streptavidin precoated (0.5 μg/well) plate, can bind Anti-CD24 Mab (HY-P99176). The ED50 for this effect is 2.899 ng/mL.
Purity & Documentation
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ATG-031 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATG-031ATG031ATG 031Otherssolid tumourshaematological malignanciesdon't eat mephagocytosisInhibitorinhibitorinhibit

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Product Name:
ATG-031
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HY-P99176
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