2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Atorvastatin Epoxy Tetrahydrofuran Impurity

Atorvastatin Epoxy Tetrahydrofuran Impurity 

Cat. No.: HY-136185
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Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

For research use only. We do not sell to patients.

Atorvastatin Epoxy Tetrahydrofuran Impurity Chemical Structure

Atorvastatin Epoxy Tetrahydrofuran Impurity Chemical Structure

CAS No. : 873950-19-7

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Atorvastatin Epoxy Tetrahydrofuran Impurity Related Antibodies

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Description

Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589)[1]. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.

In Vitro

Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction, and the endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Atorvastatin Epoxy Tetrahydrofuran Impurity Related Antibodies
Molecular Weight

449.47

Formula

C26H24FNO5
CAS No.
SMILES

O=C(C12C(C(C)C)(O)OC(O)(C3=CC=C(F)C=C3)C1(C4=CC=CC=C4)O2)NC5=CC=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Atorvastatin Epoxy Tetrahydrofuran Impurity Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atorvastatin Epoxy Tetrahydrofuran Impurity873950-19-7Drug MetaboliteoxidativedegradationproductsAtorvastatinorallyHMG-CoAreductasebloodlipidsInhibitorinhibitorinhibit

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