1. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  2. ATM/ATR
  3. ATR-IN-17

ATR-IN-17 (compound 88) is a potent ATR kinase inhibitor. ATR-IN-17 shows good anticancer activity in LoVo cells, with an IC50 of 1 nM.

For research use only. We do not sell to patients.

ATR-IN-17 Chemical Structure

ATR-IN-17 Chemical Structure

CAS No. : 2761194-15-2

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Description

ATR-IN-17 (compound 88) is a potent ATR kinase inhibitor. ATR-IN-17 shows good anticancer activity in LoVo cells, with an IC50 of 1 nM[1].

IC50 & Target

ATR

 

Molecular Weight

440.56

Formula

C22H28N6O2S

CAS No.
SMILES

CC1=NN=C(C1)C2=NSC3=C2N=C(C=C3C4(CCCCC4)C(N)=O)N5CCOC[C@H]5C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ATR-IN-17
Cat. No.:
HY-147569
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