Atriopeptin II (rat, mouse) 

Atriopeptin II rat, mouse is an atrial natriuretic peptide, which acts as diuretic and natriuretic agent, and a potent relaxant of vascular smooth muscle^[1].

Atriopeptin II rat, mouse (10 nM, 100 min) exhibits vasodilatory effect, increases cyclic GMP concentrations and activates cyclic GMP-kinase in rat ex vivo thoracic aorta^[1].
Atriopeptin II rat, mouse (0-100 nM) stimulates the testosterone production with half-maximum stimulation of 2.6 nM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2386.63

C₉₈H₁₅₆N₃₄O₃₂S₂

89139-54-8

Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg (Disulfide bridge: Cys3-Cys19)

SSCFGGRIDRIGAQSGLGCNSFR (Disulfide bridge: Cys3-Cys19)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Fiscus RR, et al., Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta. Biochim Biophys Acta. 1985 Jul 30;846(1):179-84.   [Content Brief]

  [2]. Mukhopadhyay AK, et al., Testosterone production by mouse Leydig cells is stimulated in vitro by atrial natriuretic factor. FEBS Lett. 1986 Jun 23;202(1):111-6.  [Content Brief]