2. Cell Cycle/DNA Damage Epigenetics
  3. Aurora Kinase LIM Kinase (LIMK)
  4. Aurora/LIM kinase-IN-1

Aurora/LIM kinase-IN-1 (Compound F114) is a potent and dual inhibitor of aurora and lim kinase. Aurora kinases and lim kinases are involved in neoplastic cell division and cell motility, respectively. Aurora/LIM kinase-IN-1 inhibits GBM proliferation and invasion. Aurora/LIM kinase-IN-1 is a promising new scaffold for dual aurora/lim kinase inhibitors that may be used in future agent development efforts for GBM, and potentially other cancers.

For research use only. We do not sell to patients.

Aurora/LIM kinase-IN-1 Chemical Structure

Aurora/LIM kinase-IN-1 Chemical Structure

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Aurora/LIM kinase-IN-1 Related Antibodies

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Aurora Kinase Aurora A Aurora B Aurora C

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Description

Aurora/LIM kinase-IN-1 (Compound F114) is a potent and dual inhibitor of aurora and lim kinase. Aurora kinases and lim kinases are involved in neoplastic cell division and cell motility, respectively. Aurora/LIM kinase-IN-1 inhibits GBM proliferation and invasion. Aurora/LIM kinase-IN-1 is a promising new scaffold for dual aurora/lim kinase inhibitors that may be used in future agent development efforts for GBM, and potentially other cancers[1].

Molecular Weight

312.37

Formula

C16H20N6O
SMILES

CC(N1C=C(C=N1)NC2=NC=C3C=CC(N(C3=N2)C(C)C)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Aurora/LIM kinase-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aurora/LIM kinase-IN-1Aurora KinaseLIM Kinase (LIMK)LIMKsauroralim kinaseneoplastic cell divisioncell motilityGBM proliferationinvasioncancerInhibitorinhibitorinhibit

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