2. Apoptosis Metabolic Enzyme/Protease
  3. Glutathione Peroxidase Ferroptosis
  4. AX-53802

AX-53802 is a ferroptosis inducer targeting GPX4 with an IC50 of 0.34 µM. AX-53802 forms a covalent bond with GPX4, initiating membrane translocation directly upon binding. AX-53802 and FAK/Src inhibitors promotes cell death. AX-53802 can be used for cancer study.

For research use only. We do not sell to patients.

AX-53802 Chemical Structure

AX-53802 Chemical Structure

CAS No. : 1008482-71-0

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AX-53802 Related Antibodies

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Description

AX-53802 is a ferroptosis inducer targeting GPX4 with an IC50 of 0.34 µM. AX-53802 forms a covalent bond with GPX4, initiating membrane translocation directly upon binding. AX-53802 and FAK/Src inhibitors promotes cell death. AX-53802 can be used for cancer study[1].

Molecular Weight

408.42

Formula

C23H21FN2O4
CAS No.
SMILES

O=C(NC1CCCC1)C(C2=C(F)C=CC=C2)N(C(C#C)=O)C3=CC=C4C(OCO4)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AX-53802 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AX-538021008482-71-0AX53802AX 53802Glutathione PeroxidaseFerroptosisferroptosismembrane translocationInhibitorinhibitorinhibit

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