2. Protein Tyrosine Kinase/RTK Metabolic Enzyme/Protease
  3. TAM Receptor HIF/HIF Prolyl-Hydroxylase
  4. Axl-IN-16

Axl-IN-16 is a dual inhibitor of Axl/HIF. Axl-IN-16 induces fruiting body formation of Flammulina velutipes. Axl-IN-16 inhibits hypoxia-inducible factor activity and receptor tyrosine kinase expression.

For research use only. We do not sell to patients.

Axl-IN-16 Chemical Structure

Axl-IN-16 Chemical Structure

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Axl-IN-16 Related Antibodies

Top Publications Citing Use of Products

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Axl Mer Tyro3

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HIF-1α HIF

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Description

Axl-IN-16 is a dual inhibitor of Axl/HIF. Axl-IN-16 induces fruiting body formation of Flammulina velutipes. Axl-IN-16 inhibits hypoxia-inducible factor activity and receptor tyrosine kinase expression[1].

IC50 & Target

Axl

 

Molecular Weight

350.75

Formula

C14H19ClO8
SMILES

ClC1=C(OC)C=C(C(OC[C@@H](O)[C@@H](O)[C@H](O)CO)=O)C=C1OC
Structure Classification
Initial Source

Hericium erinaceus,Monascus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Axl-IN-16 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Axl-IN-16TAM ReceptorHIF/HIF Prolyl-HydroxylaseTyro3AxlMerHypoxia-inducible factorsHIFsHIF-PHFruiting-body formation inducerAxl and immune checkpoints inhibitorHypoxia-inducible factor inhibitorInhibitorinhibitorinhibit

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