2. Anti-infection Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. Enterovirus EGFR
  4. AZ5385

AZ5385 is an EGFR-tyrosine kinase inhibitor. AZ5385 is a HRV-2 virus blocker, with EC50 of 0.35 µM. AZ5385 affects the late stage of viral life cycle.

For research use only. We do not sell to patients.

AZ5385 Chemical Structure

AZ5385 Chemical Structure

CAS No. : 848439-89-4

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AZ5385 Related Antibodies

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Description

AZ5385 is an EGFR-tyrosine kinase inhibitor. AZ5385 is a HRV-2 virus blocker, with EC50 of 0.35 µM. AZ5385 affects the late stage of viral life cycle[1].

In Vitro

AZ5385 (72 h) shows a CC50 of 9 µM for HeLa cells[1].
AZ5385 (3 h prior to the addition ofvirus, following incubation at 37°C for 72 h) also inhibits infection of HEp-2 cellscells by HRV-16, and RSV strain A2, with EC50s of 3.6 and 0.4 µM [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AZ5385 Related Antibodies
Molecular Weight

460.89

Formula

C22H22ClFN4O4
CAS No.
SMILES

C[C@H](O)C(N(CC1)CCC1OC(C(O)=C2)=CC3=C2C(NC4=C(C(Cl)=CC=C4)F)=NC=N3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AZ5385 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ5385848439-89-4AZ 5385AZ-5385EnterovirusEGFRRhinovirusHRVHRVsHEVHEVsEpidermal growth factor receptorErbB-1HER1HRV-2virusinfectionInhibitorinhibitorinhibit

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