2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. Azemiopsin

Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC50s of 0.18 μM and 22 μM against T. californica nAChR and human α7 nAChR, respectively. Azemiopsin blocks acetylcholine-induced currents in Xenopus oocytes heterologously expressing human muscle-type nAChR.

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Azemiopsin Chemical Structure

Azemiopsin Chemical Structure

CAS No. : 1391936-86-9

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Azemiopsin Related Antibodies

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Description

Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC50s of 0.18 μM and 22 μM against T. californica nAChR and human α7 nAChR, respectively. Azemiopsin blocks acetylcholine-induced currents in Xenopus oocytes heterologously expressing human muscle-type nAChR[1].

IC50 & Target

IC50: 0.18 μM (T. californica nAChR), 22 μM (Human α7 nAChR), 63 μM (L. stagnalis AChBP), 230 μM (A. californica AChBP)[1]
Molecular Weight

2540.88

Formula

C118H174N38O26
CAS No.
Sequence

Asp-Asn-Trp-Trp-Pro-Lys-Pro-Pro-His-Gln-Gly-Pro-Arg-Pro-Pro-Arg-Pro-Arg-Pro-Lys-Pro
Sequence Shortening

DNWWPKPPHQGPRPPRPRPKP
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Azemiopsin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azemiopsin1391936-86-9nAChRNicotinic acetylcholine receptorsAzemiops feaeXenopus oocytesInhibitorinhibitorinhibit

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