Azido-PEG8-Amido-Val-Cit-PAB

Cat. No.: HY-W800814: FAQs
Data Sheet Handling Instructions Technical Support

Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Azido will react with DBCO, BCN or other alkyne groups through click chemistry. PEG spacer increases aqueous solubility. Reagent grade, for research purpose.

For research use only. We do not sell to patients.

Azido-PEG8-Amido-Val-Cit-PAB Chemical Structure

CAS No. : 2356229-77-9

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Description	Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Azido will react with DBCO, BCN or other alkyne groups through click chemistry. PEG spacer increases aqueous solubility. Reagent grade, for research purpose.
Molecular Weight	916.03
Formula	C₄₀H₆₉N₉O₁₅
CAS No.	2356229-77-9
SMILES	[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)=O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (236 KB) Handling Instructions (2659 KB)