2. Membrane Transporter/Ion Channel Anti-infection
  3. Proton Pump Bacterial Fungal
  4. Bafilomycin D

Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity.

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Bafilomycin D Chemical Structure

Bafilomycin D Chemical Structure

CAS No. : 98813-13-9

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Based on 1 publication(s) in Google Scholar

Bafilomycin D Related Antibodies

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Description

Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity[1].

Molecular Weight

604.81

Formula

C35H56O8
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1O[C@H]([C@@H](C)[C@@H](O)[C@H](C)C(/C=C/[C@H](C)[C@H](O)C(C)C)=O)[C@@H](OC)/C=C/C=C(C)/C[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C=C1\OC
Structure Classification
Initial Source

Streptomyces varsoviensis
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (82.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Methanol : 6.1 mg/mL (10.09 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6534 mL 8.2671 mL 16.5341 mL
5 mM 0.3307 mL 1.6534 mL 3.3068 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.30%

SDS (251 KB)

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Methanol / DMSO 1 mM 1.6534 mL 8.2671 mL 16.5341 mL 41.3353 mL
5 mM 0.3307 mL 1.6534 mL 3.3068 mL 8.2671 mL
10 mM 0.1653 mL 0.8267 mL 1.6534 mL 4.1335 mL
DMSO 15 mM 0.1102 mL 0.5511 mL 1.1023 mL 2.7557 mL
20 mM 0.0827 mL 0.4134 mL 0.8267 mL 2.0668 mL
25 mM 0.0661 mL 0.3307 mL 0.6614 mL 1.6534 mL
30 mM 0.0551 mL 0.2756 mL 0.5511 mL 1.3778 mL
40 mM 0.0413 mL 0.2067 mL 0.4134 mL 1.0334 mL
50 mM 0.0331 mL 0.1653 mL 0.3307 mL 0.8267 mL
60 mM 0.0276 mL 0.1378 mL 0.2756 mL 0.6889 mL
80 mM 0.0207 mL 0.1033 mL 0.2067 mL 0.5167 mL
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Bafilomycin D Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bafilomycin D98813-13-9Proton PumpBacterialFungalbacteriostaticinsecticidalweedingInhibitorinhibitorinhibit

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