2. Protein Tyrosine Kinase/RTK
  3. c-Kit
  4. Barzolvolimab

Barzolvolimab  (Synonyms: CDX 0159)

Cat. No.: HY-P99462 Purity: 99.83%
COA

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Barzolvolimab (CDX 0159) is a humanized anti-KIT IgG1 monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria.

For research use only. We do not sell to patients.

CAS No. : 2438203-51-9

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1 mg USD 400 In-stock
5 mg USD 1040 In-stock
10 mg USD 1665 In-stock
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Based on 1 publication(s) in Google Scholar

Barzolvolimab Related Antibodies

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Description

Barzolvolimab (CDX 0159) is a humanized anti-KIT IgG1 monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
In Vitro

Barzolvolimab binds the extracellular domain of KIT with high specificity and sub-nanomolar affinity, and allosterically inhibits activation by stem cell factor (SCF)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Barzolvolimab Related Antibodies
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Barzolvolimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Purity & Documentation

Purity: 99.83%

COA (231 KB) SDS-PAGE (73 KB) SEC-HPLC (82 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Barzolvolimab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Barzolvolimab2438203-51-9CDX 0159CDX0159CDX-0159c-KitSCFRCD117KITIgG1monoclonal antibodySCFchronic inducible urticariaInhibitorinhibitorinhibit

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