Bay 55-9837 

Bay 55-9837 is a potent and highly selective agonist of VPAC2, with a K_d of 0.65 nM. Bay 55-9837 may be a useful therapy for the research of type 2 diabetes^[1].

Kd: 0.65 nM (VPAC2)^[1]

3740.04

C₁₄₈H₂₃₉ClN₄₄O₄₂

463930-25-8

Solid

White to off-white

His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Val-Ala-Ala-Lys-Lys-Tyr-Leu-Gln-Ser-Ile-Lys-Asn-Lys-Arg-Tyr-NH2

HSDAVFTDNYTRLRKQVAAKKYLQSIKNKRY-NH2

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Tsutsumi M, et, al. A potent and highly selective VPAC2 agonist enhances glucose-induced insulin release and glucose disposal: a potential therapy for type 2 diabetes. Diabetes. 2002 May; 51(5): 1453-60.  [Content Brief]