2. Anti-infection
  3. Bacterial
  4. BB-78485

BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials.

For research use only. We do not sell to patients.

BB-78485 Chemical Structure

BB-78485 Chemical Structure

CAS No. : 207732-11-4

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Based on 1 publication(s) in Google Scholar

BB-78485 Related Antibodies

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Description

BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials[1].
IC50 & Target

IC50: 160 nM(LpxC)[1]
In Vitro

BB-78485 can inhibit LpxC with an IC50 value of 160 nM[1].
BB-78485 has effect against D21 and D22 (lpxC101) with MICs values of 2 μg/mL and 0.016 μg/mL, respectively[1].
BB-78485 shows predominantly gram-negative activities against members of the Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae, and Burkholderia cepacia with MICs values range from 1μg/mL to 32 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BB-78485 Related Antibodies
Molecular Weight

420.48

Formula

C23H20N2O4S
CAS No.
SMILES

O=C([C@@H](CC1=CC=C2C=CC=CC2=C1)NS(=O)(C3=CC=C4C=CC=CC4=C3)=O)NO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BB-78485 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BB-78485207732-11-4BB78485BB 78485BacterialLpxCmetalloenzymeantibacterialgram-negativeInhibitorinhibitorinhibit

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HY-121021
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