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  3. BE 24566B

BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively).

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BE 24566B Chemical Structure

BE 24566B Chemical Structure

CAS No. : 149466-04-6

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Description

BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively).

Molecular Weight

460.48

Formula

C₂₇H₂₄O₇

CAS No.
SMILES

OC(C(C(C1=C2O)=O)=C(C(C)(C1=CC(O)=C2)C)C=C3C[C@@]4(C)O5)=C3[C@@]5([H])C(C(O4)=CC(O)=C6)=C6C

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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BE 24566B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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BE 24566B
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HY-W781265
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