2. Metabolic Enzyme/Protease
  3. HMG-CoA Reductase (HMGCR)
  4. Bemfivastatin hemicalcium

Bemfivastatin hemicalcium  (Synonyms: PPD 10558 hemicalcium)

Cat. No.: HY-106281A Purity: 98.00%
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Bemfivastatin (PPD 10558) hemicalcium is an orally active lipid-lowering agent and HMG-CoA reductase inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extracts. Bemfivastatin hemicalcium has no-observed adverse effect levels (NOAEL) with dosages of ≥320 mg/kg/d (rat developmental toxicity), ≥12.5 mg/kg/d (rabbit maternal toxicity), ≥25 mg/kg/d (rabbit developmental toxicity), respectively. Bemfivastatin hemicalcium can be used in the study of statin-related hypercholesterolemic myalgia in statin-intolerant patients.

For research use only. We do not sell to patients.

Bemfivastatin hemicalcium Chemical Structure

Bemfivastatin hemicalcium Chemical Structure

CAS No. : 805241-64-9

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Other Forms of Bemfivastatin hemicalcium:

Bemfivastatin hemicalcium Related Antibodies

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Description

Bemfivastatin (PPD 10558) hemicalcium is an orally active lipid-lowering agent and HMG-CoA reductase inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extracts. Bemfivastatin hemicalcium has no-observed adverse effect levels (NOAEL) with dosages of ≥320 mg/kg/d (rat developmental toxicity), ≥12.5 mg/kg/d (rabbit maternal toxicity), ≥25 mg/kg/d (rabbit developmental toxicity), respectively. Bemfivastatin hemicalcium can be used in the study of statin-related hypercholesterolemic myalgia in statin-intolerant patients.

Molecular Weight

607.74

Formula

C34H37FN2O6.1/2Ca
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[O-]C(C[C@H](O)C[C@H](O)CCN1C(C2=CC=C(F)C=C2)=C(C3=CC=CC=C3)C(C(NC4=CC=C(CO)C=C4)=O)=C1C(C)C)=O.[Ca+2].[1/2]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

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Bemfivastatin hemicalcium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bemfivastatin hemicalcium805241-64-9PPD 10558 hemicalciumHMG-CoA Reductase (HMGCR)Inhibitorinhibitorinhibit

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