Benzoctamine hydrochloride (Synonyms: Ba-30803)

Cat. No.: HY-A0171A: FAQs
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Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain.

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Benzoctamine hydrochloride Chemical Structure

CAS No. : 10085-81-1

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Other Forms of Benzoctamine hydrochloride:

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Purity & Documentation
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Description	Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain^[1]^[2].
In Vivo	Benzoctamine hydrochloride (Ba-30803) inhibits the head twitch reaction induced by L-5-hydroxytryptophan (5-HTP) in mice and by 5-methoxytryptamine (5-MT) in rats pretreated with tranylcypromine. Benzoctamine also antagonizes tryptamine (TRP)-induced clonic convulsions of forepaws in rats ^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	285.81
Formula	C₁₈H₂₀ClN
CAS No.	10085-81-1
SMILES	CNCC12C3=C(C=CC=C3)C(CC2)C4=CC=CC=C14.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Lippmann W, et al. Effects of benzoctamine and chlordiazepoxide on turnover and uptake of 5-hydroxytryptamine in the brain. Br J Pharmacol. 1974;51(4):571-575. [Content Brief] [2]. Przegaliński E, et al. On the central antiserotonin activity of benzoctamine and opipramol. Pol J Pharmacol Pharm. 1978;30(6):781-790. [Content Brief]

Benzoctamine hydrochloride Related Classifications

Neurological Disease

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Benzoctamine10085-81-1Ba-30803Ba30803Ba 308035-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorturnoveruptakebrainstressanxietyInhibitorinhibitorinhibit

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