2. GPCR/G Protein TGF-beta/Smad Stem Cell/Wnt
  3. Prostaglandin Receptor PKA
  4. BGC-20-1531

BGC-20-1531 (PGN 1531), a benzenesulfonamide derivative, is a selective EP4 antagonist. BGC-20-1531 binds to PGE2 enhancing the ATPase activity, which are coupled to Gs proteins and thus activate adenylate cyclase generating cAMP and activating PKA. BGC-20-1531 is promising for research of liver disorders.

For research use only. We do not sell to patients.

BGC-20-1531 Chemical Structure

BGC-20-1531 Chemical Structure

CAS No. : 1186532-61-5

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BGC-20-1531 Related Antibodies

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Description

BGC-20-1531 (PGN 1531), a benzenesulfonamide derivative, is a selective EP4 antagonist. BGC-20-1531 binds to PGE2 enhancing the ATPase activity, which are coupled to Gs proteins and thus activate adenylate cyclase generating cAMP and activating PKA. BGC-20-1531 is promising for research of liver disorders[1][2].

IC50 & Target

EP4

 

Molecular Weight

514.53

Formula

C26H23N2NaO6S
CAS No.
SMILES

O=C(C1=CC(COC2=CC=C(C3=NC=C(C=C3)OC)C=C2)=C(C)O1)N([Na])S(=O)(C4=C(C)C=CC=C4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BGC-20-1531 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BGC-20-15311186532-61-5PGN 1531PGN1531PGN-1531Prostaglandin ReceptorPKAProtein kinase Abenzenesulfonamide derivativeEP4ATPase activityGs proteinsInhibitorinhibitorinhibit

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