2. GPCR/G Protein
  3. Free Fatty Acid Receptor
  4. BI-2081

BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2.

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BI-2081 Chemical Structure

BI-2081 Chemical Structure

CAS No. : 1458656-71-7

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BI-2081 Related Antibodies

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Description

BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2[1].

IC50 & Target

GPR40 (FFAR1)[1]
Molecular Weight

534.62

Formula

C32H35FO6
CAS No.
SMILES

FC1=C(C(CC2)=C(C3=C(C=C(C=C3C)OCCC(C)(O)C)C)C=C1)[C@@H]2OC4=CC=C([C@@H](CO5)CC(O)=O)C5=C4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BI-2081 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BI-20811458656-71-7BI2081BI 2081Free Fatty Acid ReceptorFFARInsulinglucosetype 2 diabetesInhibitorinhibitorinhibit

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HY-148247
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