2. Protein Tyrosine Kinase/RTK
  3. Syk
  4. BI1002494

BI1002494 is an orally active, potent, and selective spleen tyrosine kinase (SYK) inhibitor. BI 1002494 exhibits an IC50 of 115 nM in inhibiting high-affinity IgE receptor-mediated mast cell and basophil degranulation. BI1002494 can be utilized in immunology reesearch.

For research use only. We do not sell to patients.

BI1002494 Chemical Structure

BI1002494 Chemical Structure

CAS No. : 1319738-39-0

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BI1002494 Related Antibodies

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Description

BI1002494 is an orally active, potent, and selective spleen tyrosine kinase (SYK) inhibitor. BI 1002494 exhibits an IC50 of 115 nM in inhibiting high-affinity IgE receptor-mediated mast cell and basophil degranulation. BI1002494 can be utilized in immunology reesearch[1].

Molecular Weight

423.46

Formula

C23H25N3O5
CAS No.
SMILES

O=C1NC[C@@H](C1)[C@@H](C)OC2=C3C=CC=NC3=CC(C4=CC(OC)=C(C(OC)=C4)OC)=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BI1002494 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BI10024941319738-39-0BI 1002494BI-1002494SykSpleen tyrosine kinasespleen tyrosine kinase inhibitorhigh-affinity IgE receptordegranulationInhibitorinhibitorinhibit

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