2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. BIBO3304 free base

BIBO3304 free base is a nonpeptide neuropeptide Y Y1 receptor antagonist. BIBO3304 free base displays subnanomolar affinity for both the human and the rat Y1 receptor, with IC50 values of 0.38 nM and 0.72 nM, respectively. BIBO3304 free base significantly inhibits food intake induced by application of NPY or by fasting.

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BIBO3304 free base Chemical Structure

BIBO3304 free base Chemical Structure

CAS No. : 191868-13-0

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BIBO3304 free base Related Antibodies

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Description

BIBO3304 free base is a nonpeptide neuropeptide Y Y1 receptor antagonist. BIBO3304 free base displays subnanomolar affinity for both the human and the rat Y1 receptor, with IC50 values of 0.38 nM and 0.72 nM, respectively. BIBO3304 free base significantly inhibits food intake induced by application of NPY or by fasting[1].

Molecular Weight

529.63

Formula

C29H35N7O3
CAS No.
SMILES

O=C([C@@H](CCC/N=C(N)\N)NC(C(C1=CC=CC=C1)C2=CC=CC=C2)=O)NCC3=CC=C(C=C3)CNC(N)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BIBO3304 free base Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BIBO3304191868-13-0BIBO 3304BIBO-3304Neuropeptide Y ReceptorNPY receptorNonpeptidesubnanomolar affinityfood intakefastingNPYInhibitorinhibitorinhibit

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