2. GPCR/G Protein
  3. GPR171
  4. BigLEN(rat)

BigLEN(rat) is a potent GPR171 agonist with an EC50 of 1.6 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

BigLEN(rat) Chemical Structure

BigLEN(rat) Chemical Structure

CAS No. : 369377-66-2

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Based on 1 publication(s) in Google Scholar

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BigLEN(rat) Related Antibodies

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Description

BigLEN(rat) is a potent GPR171 agonist with an EC50 of 1.6 nM[1].

IC50 & Target

EC50: 1.6 nM (GPR171)[1]
Molecular Weight

1745.98

Formula

C76H128N24O23
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Leu-Glu-Asn-Ser-Ser-Pro-Gln-Ala-Pro-Ala-Arg-Arg-Leu-Leu-Pro-Pro
Sequence Shortening

LENSSPQAPARRLLPP
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (28.64 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5727 mL 2.8637 mL 5.7274 mL
5 mM 0.1145 mL 0.5727 mL 1.1455 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5727 mL 2.8637 mL 5.7274 mL 14.3186 mL
5 mM 0.1145 mL 0.5727 mL 1.1455 mL 2.8637 mL
10 mM 0.0573 mL 0.2864 mL 0.5727 mL 1.4319 mL
15 mM 0.0382 mL 0.1909 mL 0.3818 mL 0.9546 mL
20 mM 0.0286 mL 0.1432 mL 0.2864 mL 0.7159 mL
25 mM 0.0229 mL 0.1145 mL 0.2291 mL 0.5727 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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BigLEN(rat) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BigLEN(rat)369377-66-2GPR171G Protein-Coupled Receptor 171Inhibitorinhibitorinhibit

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