HSP Inhibitors

HSP40

HSP70

HSP90

HSP105

HSF1

HSP

HSPA5

HSP Inducers, Inhibitors, Antagonists & Activators

Product Name	HSP40	HSP70	HSP90	HSP105	HSF1	HSP	HSPA5	Purity
Tamoxifen			HSP90					99.92%
Polyinosinic-polycytidylic acid		HSP70						99.40%
Tanespimycin			HSP90, IC₅₀: 5 nM					99.01%
VER-155008		HSP70, IC₅₀: 0.5 μM HSC70, IC₅₀: 2.6 μM Grp78, IC₅₀: 2.6 μM						99.91%
SNX-5422 mesylate			HSP90, Kd: 41 nM
Zelavespib formic			HSP90, IC₅₀: 51 nM
Geldanamycin			HSP90, Kd: 1.2 μM					99.78%
Tamoxifen Citrate			HSP90					99.93%
Ganetespib			HSP90					99.94%
Luminespib			HSP90α, IC₅₀: 7.8 nM HSP90β, IC₅₀: 21 nM GRP94, IC₅₀: 535 nM					99.81%
Gamitrinib TPP hexafluorophosphate			HSP90					99.12%
Novobiocin sodium			HSP90					99.12%
Rocaglamide					HSF1, IC₅₀: 50 nM			99.34%
Onalespib			HSP90, Kd: 0.71 nM					99.62%
Apoptozole		HSP70, Kd: 0.14 μM HSC70, Kd: 0.21 μM						99.42%
Pifithrin-μ		HSP70						99.66%
Alvespimycin hydrochloride			HSP90, EC₅₀: 62 nM GRP94, EC₅₀: 65 nM					99.55%
Pimitespib			HSP90α, Ki: 34.7 nM HSP90β, Ki: 21.3 nM					98.79%
KRIBB11					HSF1, IC₅₀: 1.2 μM			99.54%
Col003	HSP47, IC₅₀: 1.8 μM							99.87%
HSF1A					HSF1			99.46%
MKT-077		HSP70						98.05%
BIIB021			HSP90, Ki: 1.7 nM HSP90, EC₅₀: 38 nM					99.19%
Tamoxifen (Standard)			HSP90					99.76%
NXP800					HSF1			99.79%
Grp94 Inhibitor-1			GRP94, IC₅₀: 2 nM					98.72%
Teprenone						HSP		99.58%
Arimoclomol maleate						HSP		99.96%
ML346		HSP70, EC₅₀: 4.6 μM (HeLa cells)						98.71%
Alvespimycin			HSP90, EC₅₀: 62 nM GRP94, EC₅₀: 65 nM					99.59%
XL888			HSP90, IC₅₀: 24 nM					99.39%
AMP-PCP disodium			HSP90, Kd: 3.8 μM					99.29%
KNK437	HSP40	HSP70		HSP105				≥98.0%
NVP-HSP990			HSP90α, IC₅₀: 0.6 nM HSP90β, IC₅₀: 0.8 nM GRP94, IC₅₀: 8.5 nM					99.49%
Retaspimycin Hydrochloride			HSP90, EC₅₀: 119 nM GRP94, EC₅₀: 119 nM
Zelavespib			HSP90, IC₅₀: 51 nM (MDA-MB-468 cells)					99.93%
Radicicol			HSP90, IC₅₀: 1 μM					99.63%
CCT251236		HSP72, IC₅₀: 19 nM (SK-OV-3 cells)						98.82%
Debio 0932			HSP90α, IC₅₀: 100 nM HSP90β, IC₅₀: 103 nM					99.97%
Smurf1-IN-A01			HSP90β					99.81%
SNX-2112		TRAP-1, IC₅₀: 862 nM	HSP90α, IC₅₀: 30 nM HSP90β, IC₅₀: 30 nM GRP94, IC₅₀: 4275 nM					99.45%
HM03							HSPA5	99.34%
PU-WS13			GRP94, EC₅₀: 0.22 μM HSP90α, EC₅₀: 27.3 μM HSP90β, EC₅₀: 41.8 μM					99.94%
Chetomin			HSP90					≥99.0%
VER-82576			HSP90β, IC₅₀: 58 nM GRP94, IC₅₀: 4.1 μM					98.76%
TRC051384		HSP70						98.01%
KW-2478			HSP90α, IC₅₀: 3.8 nM					99.90%
Cucurbitacin D			HSP90					99.91%
CCT018159			human Hsp90β, IC₅₀: 3.2 μM yeast Hsp90, IC₅₀: 6.6 μM					99.94%
Dihydroberberine			HSP90					98.44%
Novobiocin			HSP90
VER-49009			HSP90, IC₅₀: 25 nM					99.45%
PROTAC HSP90 degrader BP3			HSP90					98.56%
Eupalinolide A					HSF1			99.92%
NMS-E973			HSP90α, DC₅₀: 10 nM					98.57%
Geldanamycin-FITC			HSP90					98.43%
MAL3-101		HSP70						98.22%
VER-50589			HSP90, IC₅₀: 21 nM					99.76%
JG-231		HSP70						98.81%
Ethoxyquin			HSP90					98.32%
NCT-58			HSP90					99.82%
AT-533			HSP90					98.86%
3-Phenyltoxoflavin			HSP90, Kd: 585 nM					99.86%
CH5138303			HSP90α, Kd: 0.52 nM					99.05%
YK5		HSP70	HSP90					99.66%
HSP70-IN-1		HSP70						98.05%
GRP78-IN-3							HSPA5, IC₅₀: 0.59 μM	99.98%
Bimoclomol						HSP		99.29%
Zelavespib hydrochloride			HSP90, IC₅₀: 51 nM (MDA-MB-468 cells)					98.89%
HS-27			HSP90					98.48%
Tamoxifen-d₅			HSP90					99.99%
YZ129			HSP90					99.85%
Gedunin			HSP90					≥98.0%
Gamitrinib TPP			HSP90
SW02		TRAP1 ATPase, EC₅₀: 150 ± 21 μM						98.30%
Aminohexylgeldanamycin			HSP90					99.56%
DN401			HSP90, IC₅₀: 698 nM					≥99.0%
Conglobatin			HSP90
Arimoclomol						HSP
Arimoclomol citrate						HSP
HSP90/mTOR-IN-1			HSP90, IC₅₀: 69 nM
Onalespib lactate			HSP90, Kd: 0.71 nM
Cemdomespib			HSP90
Shepherdin (79-87)			HSP90
Gamendazole			HSP90AB1
BX-2819			HSP90, IC₅₀: 41 nM
EZH2/HSP90-IN-29			HSP90, IC₅₀: 60.1 nM
Macbecin			HSP90, IC₅₀: 2 μM HSP90, Kd: 0.24 μM
EV206		HSP70
HSP90/LSD1-IN-1			HSP90
AP-4-139B		HSP70, IC₅₀: 180 nM
HSP90-IN-20			HSP90, IC₅₀: ≤10 μM
Colletofragarone A2			HSP90
Aminohexylgeldanamycin hydrochloride			HSP90
YM-08		HSP70
DMT003096		HSP70
Hsp90-IN-15			HSP90
HSP70-IN-6		HSP70
HSP90-IN-33			HSP90α, EC₅₀: ≥200 μM HSP90β, EC₅₀: 7.3 μM
HSP90-IN-13			HSP90, IC₅₀: 25.07 nM
Rosolutamide					HSF1
Tasiamide B			HSP90
KU-177			HSP90
HSP90-IN-9			HSP90
Antitumor agent-174			HSP90
MAO A/HSP90-IN-2			HSP90, IC₅₀: 0.016 μM
HDAC/HSP90-IN-3			HSP90, IC₅₀: 0.83 μM (fungal Hsp90) HSP90, IC₅₀: 19.52 μM (human Hsp90)
17-AEP-GA			HSP90
GRP78-IN-1		Grp78
HDAC6/HSP90-IN-1			HSP90, IC₅₀: 46.8 nM
Grp94 Inhibitor-2			GRP94, Kd: 0.48 nM HSP90α, Kd: 0.65 nM
HSP70/SIRT2-IN-1		HSP70
17-GMB-APA-GA			HSP90
HSP90-IN-14			HSP90β, Kd: 0.26 ± 0.0 μM
HSP70-IN-4		HSP70, IC₅₀: 3.2 μM
AMP-PCP			HSP90, Kd: 3.8 μM
PU24FCl			HSP90
MPC-0767			HSP90
MAO A/HSP90-IN-1			HSP90, IC₅₀: 0.019 μM
HSP90-IN-29			HSP90, IC₅₀: 30 nM
Retaspimycin			HSP90, EC₅₀: 119 nM GRP94, EC₅₀: 119 nM

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