Acetyl-coenzyme A transporter 1

Definition:

Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides. Negatively regulates BMP signaling.

References:

[1]. Fei Mao, et al. Identification and functional analysis of a SLC33A1: c.339T>G (p.Ser113Arg) variant in the original SPG42 family. Hum Mutat. 2015 Feb;36(2):240-9. [Content Brief]

[2]. A Kanamori, et al. Expression cloning and characterization of a cDNA encoding a novel membrane protein required for the formation of O-acetylated ganglioside: a putative acetyl-CoA transporter. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2897-902. [Content Brief]

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