Acrokeratosis verruciformis

Definition:

Acrokeratosis verruciformis is a rare autosomal dominant genodermatosis characterized by multiple planar wart-like lesions on the hands and feet. The lesions are usually present at birth. Mutations in ATP2A2 encoding the calcium pump in sarcoendoplasmic reticulum have been identified.

References:

[1]. Chul Hwan Bang, et al. Non-familial Acrokeratosis Verruciformis of Hopf. Ann Dermatol. 2011 Sep;23 Suppl 1(Suppl 1):S61-3. [Content Brief]

[2]. Jittima Dhitavat, et al. Acrokeratosis verruciformis of Hopf is caused by mutation in ATP2A2: evidence that it is allelic to Darier's disease. J Invest Dermatol. 2003 Feb;120(2):229-32. [Content Brief]

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