Acylpyruvase FAHD1, mitochondrial

Definition:

Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity.

References:

[1]. Babu A Manjasetty, et al. X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880. Biol Chem. 2004 Oct;385(10):935-42. [Content Brief]

[2]. Haymo Pircher, et al. Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase. J Biol Chem. 2015 Mar 13;290(11):6755-62. [Content Brief]

[3]. Haymo Pircher, et al. Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. J Biol Chem. 2011 Oct 21;286(42):36500-8. [Content Brief]

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