Adenine nucleotide translocase lysine N-methyltransferase

Definition:

Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration. Probably also trimethylates ANT1/SLC25A4.

References:

[1]. Jędrzej M Małecki, et al. Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration. J Biol Chem. 2019 Aug 2;294(31):11654-11664. [Content Brief]

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