Adenylate kinase 8

Definition:

Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.

References:

[1]. Marjan Amiri, et al. The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase. Int J Biochem Cell Biol. 2013 May;45(5):925-31. [Content Brief]

[2]. Christakis Panayiotou, et al. The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes. Biochem J. 2011 Feb 1;433(3):527-34. [Content Brief]

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