Aquaporin-9

Definition:

Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines.

References:

[1]. Kamil Gotfryd, et al. Human adipose glycerol flux is regulated by a pH gate in AQP10. Nat Commun. 2018 Nov 12;9(1):4749. [Content Brief]

[2]. H Tsukaguchi, et al. Functional and molecular characterization of the human neutral solute channel aquaporin-9. Am J Physiol. 1999 Nov;277(5):F685-96. [Content Brief]

[3]. K Ishibashi, et al. Cloning and functional expression of a new aquaporin (AQP9) abundantly expressed in the peripheral leukocytes permeable to water and urea, but not to glycerol. Biochem Biophys Res Commun. 1998 Mar 6;244(1):268-74. [Content Brief]

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