Dedicator of cytokinesis protein 6

Definition:

Acts as guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth (By similarity).

References:

[1]. Yuki Miyamoto, et al. Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth. Exp Cell Res. 2007 Feb 15;313(4):791-804. [Content Brief]

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