DNA methyltransferases (DNMTs)

Definition:

DNA methyltransferases (DNMTs) is involved for DNA methylation, which are responsible for adding a methyl group to the fifth carbon atom of the cytosine residues within cytosine-phosphate-guanine (CpG) and non-CpG dinuclotide sites. Five DNMT enzymes have been identified in mammals including DNMT1, DNMT2, DNMT3A, DNMT3B, and DNMT3L. DNMTs can be used for the research of epigenetic mechanisms.

References:

[1]. Albert Jeltsch, et al. Editorial-Role of DNA Methyltransferases in the Epigenome.Genes (Basel). 2019 Jul 30;10(8):574. [Content Brief]

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